Research Topic · Peer-Reviewed

Inflammation Mediators

Inflammation mediators are the signalling molecules released during the body's response to injury, infection, or other harmful stimuli, coordinating the changes that characterise inflammation. They include cytokines, chemokines, prostaglandins, histamine, complement proteins, and reactive species, which together inc…

Curated from this journal's research 📚 4 peer-reviewed articles cited Cited 25× across the literature 🗓 Reviewed June 2026

Overview

Inflammation mediators are the signalling molecules released during the body's response to injury, infection, or other harmful stimuli, coordinating the changes that characterise inflammation. They include cytokines, chemokines, prostaglandins, histamine, complement proteins, and reactive species, which together increase blood flow, recruit immune cells, and produce the classic features of redness, heat, swelling, and pain. These mediators are essential to host defence and tissue repair, but their excessive or sustained release contributes to chronic inflammatory and immune-mediated diseases, making them important targets for anti-inflammatory and immunomodulatory therapies. Understanding how mediators such as NF-kB-driven cytokines, interleukins, and tumour necrosis factor are produced and regulated is central to inflammation research. The journal International Journal of Inflammation Research publishes peer-reviewed work on the molecular and cellular basis of inflammation and on strategies to modulate it. Within the broader OpenAccessPub collection, related studies examine pro-inflammatory signalling in keratinocytes via NF-kB inhibition, dietary fatty acids and inflammatory status in adipose tissue, plant-derived analgesic and anti-pyretic activity, and the expression of inflammatory cytokines including IL-6 and TNF-alpha in experimental models. This page gathers open-access scholarship relevant to the biology and regulation of inflammation mediators.

Research published in this journal

4 peer-reviewed articles, ranked by relevance. Each links to its DOI.

How this research is being cited

The 4 articles above have been cited 25 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Inflammation Mediators, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in International Journal of Inflammation Research.

Journal editorial board
Thomas Boldicke · Germany Graziella Curtale · Italy Frederic Velard · France

This page summarises published research for orientation; it is not medical or professional advice.