Research Topic · Peer-Reviewed

Chronic Inflammation

Chronic inflammation is a prolonged, persistent inflammatory response in which the body's immune system remains activated over weeks, months, or years, rather than resolving after the short-term reaction that normally follows injury or infection. While acute inflammation is a protective process, sustained inflammati…

Curated from this journal's research 📚 12 peer-reviewed articles cited Cited 36× across the literature 🗓 Reviewed June 2026

Overview

Chronic inflammation is a prolonged, persistent inflammatory response in which the body's immune system remains activated over weeks, months, or years, rather than resolving after the short-term reaction that normally follows injury or infection. While acute inflammation is a protective process, sustained inflammation can damage healthy tissue, disrupt normal organ function, and contribute to a wide range of diseases. It is implicated in conditions such as cardiovascular disease, diabetes, certain cancers, neurodegenerative disorders, and chronic pain, and it is influenced by factors including diet, the microbiome, and persistent immune stimulation. Understanding and managing chronic inflammation is therefore central to the prevention and treatment of many long-term illnesses. Research relevant to this topic includes work on developing cellular and molecular biomarkers for the anti-inflammatory activities of probiotic bacteria in fermented foods, a study of auricular vagus nerve stimulation showing improvement in chronic pain alongside changes in pain-related cytokine levels, and an examination of how knowledge of the microbiota may help establish an optimal diet for maintaining health. Additional work has explored the relationship between frailty and the immune system. This page gathers peer-reviewed, open-access research relevant to the mechanisms, consequences, and management of chronic inflammation.

Research published in this journal

12 peer-reviewed articles, ranked by relevance. Each links to its DOI.

How this research is being cited

The 12 articles above have been cited 36 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Chronic Inflammation, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in International Journal of Inflammation Research.

Journal editorial board
Thomas Boldicke · Germany Graziella Curtale · Italy Frederic Velard · France

This page summarises published research for orientation; it is not medical or professional advice.