Overview
Anti-inflammatory drugs are medications that reduce inflammation, the body's protective response to injury, infection, or irritation that produces pain, redness, heat, and swelling. They are broadly divided into nonsteroidal anti-inflammatory drugs (NSAIDs), which act largely by inhibiting cyclooxygenase enzymes and the production of prostaglandins, and corticosteroids, which suppress inflammation through broader effects on gene expression and immune signaling. Newer biologic and targeted agents block specific inflammatory mediators or pathways. These drugs are used to relieve pain and stiffness and to control inflammatory conditions such as arthritis, and selective COX-2 inhibitors were developed to reduce some gastrointestinal effects, although cross-reactive hypersensitivity to NSAIDs remains a clinical consideration. The International Journal of Inflammation Research, the OpenAccessPub journal hosting this page, publishes peer-reviewed, open-access research on inflammation and its treatment. Related OpenAccessPub work has reviewed the status of nonsteroidal anti-inflammatory drugs in colorectal cancer prevention, described a novel N-pyrrolylcarboxylic acid derivative as a potential analgesic and anti-inflammatory agent, and examined cross-reactivity between COX-2 inhibitors in patients with hypersensitivity to NSAIDs. This page gathers open-access scholarship relevant to anti-inflammatory drugs, their mechanisms, and their clinical use.
Research published in this journal
12 peer-reviewed articles, ranked by relevance. Each links to its DOI.
How this research is being cited
The 12 articles above have been cited 61 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
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Rupam Saha et al. · 2025 · Medicine in Novel Technology and Devices
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Ibrahim Halil Kenger et al. · 2025 · Journal of Applied Toxicology
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Yuping Zhang et al. · 2025 · Biomaterials
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Osahon Daniel Abu et al. · 2025 · Trends in Pharmacology and Toxicology
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2025 · Journal of Applied Toxicology
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2025 · Biomaterials
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2025 · Medicine in Novel Technology and Devices
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2025 · Trends in Biological Sciences
A sample of recent works citing this journal's research on Anti-inflammatory Drugs, linking to each citing work.