Overview
Clinical trials are prospective research studies that evaluate the efficacy and safety of medications, treatments, biologics, and medical devices in human participants under controlled conditions. They are the central mechanism by which a candidate intervention moves from laboratory and preclinical work into routine clinical use, typically progressing through sequential phases that establish safety, determine appropriate dosing, measure effectiveness against a comparator, and monitor longer-term outcomes after approval. Methodological safeguards such as randomization, the use of control groups, and blinding of participants and investigators reduce bias and strengthen the validity of the conclusions drawn. Findings from clinical trials inform regulatory decisions, clinical guidelines, and the identification of adverse effects, and they underpin advances in diagnosis, prevention, and management of disease. Peer-reviewed research within this journal collection addresses these themes directly: work examines the early adoption of blinding in therapeutic clinical research of neurological disorders, argues why new drugs, treatments, and medical devices must still be tested clinically before reaching the market, and reports a meta-analysis of the therapeutic antibody trastuzumab in HER2-positive advanced gastric cancer, alongside analyses of COVID-19 vaccine development. This page gathers peer-reviewed, open-access articles relevant to the design, conduct, and interpretation of clinical trials.
Research published in this journal
12 peer-reviewed articles, ranked by relevance. Each links to its DOI.
How this research is being cited
The 12 articles above have been cited 14 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
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2026 · Foods
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2025 · Journal of Biomolecular Structure and Dynamics
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M. Romdhoni et al. · 2025 · Avicenna journal of medical biotechnology
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2024 · Pharmaceuticals
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2024 · Pharmaceuticals
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2023 · Journal of Biomolecular Structure and Dynamics
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2020 · INTERNATIONAL JOURNAL OF ENDORSING HEALTH SCIENCE RESEARCH (IJEHSR)
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2020 · Jurnal Administrasi Kesehatan Indonesia
A sample of recent works citing this journal's research on Clinical Trials, linking to each citing work.