Overview
Hemodilution is the reduction of the concentration of red blood cells and other components in the blood, achieved by increasing plasma volume or replacing removed blood with fluids such as crystalloids, colloids, or plasma. In medicine it is most often used deliberately as acute normovolemic hemodilution, in which a volume of the patient's own blood is removed before or during surgery and replaced with fluid, so that blood lost during the operation contains fewer red cells; the collected blood is then returned to the patient afterward. This technique can reduce the need for allogeneic transfusion and its associated risks, and is applied particularly in procedures with anticipated significant blood loss. Hemodilution also affects blood viscosity and oxygen-carrying capacity, which must be carefully balanced. This page gathers peer-reviewed, open-access research relevant to hemodilution and transfusion medicine published in the International Journal of Blood Transfusion and related OpenAccessPub journals. On-topic work includes a prospective randomized study of acute normovolemic hemodilution in complex cardiac surgery, which examines the use of the technique in a setting of substantial potential blood loss. Together with the journal's broader coverage of blood transfusion and hematology, this material reflects the role of hemodilution as a blood-conservation strategy in surgical and transfusion practice.
Research published in this journal
4 peer-reviewed articles, ranked by relevance. Each links to its DOI.
How this research is being cited
The 4 articles above have been cited 3 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
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A. Malinowski et al. · 2021 · British Journal of Haematology
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2021 · British Journal of Haematology
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2015 · Journal of Woman s Reproductive Health
A sample of recent works citing this journal's research on Hemodilution, linking to each citing work.