Research Topic · Peer-Reviewed

Blood Coagulation

Blood coagulation is the physiological process by which blood changes from a liquid to a gel, forming a clot that stops bleeding from a damaged vessel. It proceeds through a tightly regulated sequence in which platelets first adhere and aggregate at the site of injury, followed by activation of a cascade of clotting…

Curated from this journal's research 📚 8 peer-reviewed articles cited Cited 21× across the literature 🔖 ISSN 3070-1937 🗓 Reviewed June 2026

Overview

Blood coagulation is the physiological process by which blood changes from a liquid to a gel, forming a clot that stops bleeding from a damaged vessel. It proceeds through a tightly regulated sequence in which platelets first adhere and aggregate at the site of injury, followed by activation of a cascade of clotting factors that culminates in the enzyme thrombin converting soluble fibrinogen into insoluble fibrin, the protein mesh that stabilizes the clot. Coagulation is balanced by anticoagulant and fibrinolytic systems that prevent excessive clotting and dissolve clots once healing is underway, and disturbances in this balance lead either to bleeding disorders or to dangerous thrombosis. In the context of blood transfusion, understanding coagulation is essential for managing patients with bleeding, for preparing and storing blood components such as platelets and plasma, and for correcting clotting deficiencies. Research relevant to this field includes work on inherited bleeding disorders caused by genetic mutations in blood coagulation factors and regulatory proteins, on the storage biology of platelets such as the relationship between glucose and platelet apoptosis, and on hemostatic management in cardiac surgery. This page reflects the scope of transfusion medicine in addressing hemostasis and gathers peer-reviewed, open-access material relevant to blood coagulation and its disorders.

Research published in this journal

8 peer-reviewed articles, ranked by relevance. Each links to its DOI.

How this research is being cited

The 8 articles above have been cited 21 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Blood Coagulation, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in International Journal of Blood Transfusion (ISSN 3070-1937).

Journal editorial board
PROF OSARO ERHABOR · United Kingdom Nobu Akiyama · Japan Young-Kyun Lee · South Korea

This page summarises published research for orientation; it is not medical or professional advice.